

Chronic kidney disease develops over time. It may occur because of an inherited susceptibility to kidney disease, such as in the case of polycystic kidney disease, or as the result of other conditions such as diabetes or hypertension.
Hypertension: occurs when chronically high blood pressure is forced against blood vessel walls and damages the intricate vasculature of the kidney.
Obstructions in the urinary tract: caused by tumors, kidney stones or an enlarged prostate (in males).
Polycystic kidney disease: an inherited disease which causes large cysts to form and expand in the kidneys, resulting in a loss of functional renal tubules.
Glomerulonephritis: a group of diseases that cause inflammation of the kidneys' glomeruli, which may be caused by a systemic disease such as a streptococcal infection or can be a disease itself.
Recurrent urinary infections
Diabetes: occurs when the body fails to produce and utilize insulin that is necessary in order to stabilize blood glucose levels. High blood sugar causes damage to the kidneys and other organs.
Developmental malformations: cause abnormal conditions of the urinary tract.
Autoimmune diseases: diseases, such as lupus, that affect the immune system of the entire body.

|